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October 16, 2015AJP Heart and Circulatory PhysiologyOpen Access

Phase synchrony analysis in AF reveals conserved spiral waves surrounded by disorganized tissue.

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Population

24 patients in atrial fibrillation and in silico computer simulation models

Design

Other

Key result

Phase synchrony analysis in 24 patients with atrial fibrillation demonstrated spatial organization consistent with conserved spiral waves surrounded by disorganized tissue.

Authors

DVDavid VidmarSNSanjiv M. NarayanWRWouter‐Jan Rappel

Discussion

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Overview

May refine AF mapping strategies; leaves open whether hierarchical sources sustain clinical AF.

Study Design

Type

Observational (n=24)

Structured PICO

P
Population
24 patients with atrial fibrillation undergoing multielectrode catheter mapping to assess spatial organization.
E
Exposure
Phase synchrony analysis of multielectrode catheter recordings; pharmaceutical intervention with ibutilide
O
Outcome
Spatial organization and phase synchrony of atrial fibrillationsurrogate

Phase synchrony analysis reveals that human atrial fibrillation exhibits spatial organization consistent with spiral wave mechanisms rather than multiwavelet reentry.

Cite This Study

Vidmar et al. (2015) conducted an observational in Atrial fibrillation (n=24). Phase synchrony analysis was evaluated on Spatial organization and phase synchrony. Phase synchrony analysis in 24 patients with atrial fibrillation demonstrated spatial organization consistent with conserved spiral waves surrounded by disorganized tissue.

synapsesocial.com/papers/6aa638c76cd58dd9e9f4db34https://doi.org/10.1152/ajpheart.00407.2015
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