Key result
Hand-sewn trileaflet valved conduits linked to ~57% lower graft failure risk versus bovine jugular veins.
Why the study?
Does a simplified hand-sewn trileaflet valved conduit reduce graft failure and complications compared to Bovine jugular vein grafts in patients undergoing right ventricular outflow tract reconstruction?
Population
68 patients undergoing right ventricular outflow tract (RVOT) reconstruction (total 76 conduits implanted)
Comparison
Simplified hand-sewn trileaflet valved conduit… vs Bovine jugular vein (BJV) grafts (n=54 conduits)
Design
Cohort
Follow-up
up to 7 years
Authors
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May be associated with lower graft failure; leaves open need for randomized confirmation before practice change.
Cohort (n=68)
No
Does a simplified hand-sewn trileaflet valved conduit reduce graft failure and complications compared to Bovine jugular vein grafts in patients undergoing right ventricular outflow tract reconstruction?
Absolute Event Rate: 83.6% vs 62.1%
A novel simplified hand-sewn trileaflet valved conduit may offer lower rates of graft failure, perioperative complications, and endocarditis compared to conventional bovine jugular vein grafts for RVOT reconstruction.
Zhang et al. (2017) conducted a cohort in Right ventricular outflow tract reconstruction (n=68). Simplified hand-sewn trileaflet valved conduit vs. Bovine jugular vein (BJV) graft was evaluated on Freedom from graft failure at 7 years. Simplified hand-sewn trileaflet valved conduits for right ventricular outflow tract reconstruction yielded 83.6% freedom from graft failure at 7 years versus 62.1% for bovine jugular vein grafts.
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