Key result
EMC viral infection triggers virocytonecrosis in newborn mice via intracellular membrane proliferation.
Population
Newborn mice
Design
Preclinical
Authors
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Virocytonecrosis describes EMC cytopathy in newborn mice; leaves open relevance to human enteroviral myocarditis.
EMC viral infection in newborn mice induces a specific cytopathic response termed virocytonecrosis, similar to other picornaviruses.
Burch et al. (1974) studied EMC viral infection. EMC virus infection was evaluated on Ultrastructural cyto-pathologic response. EMC viral infection in newborn mice produced specific ultrastructural cyto-pathologic responses characterized by intracellular proliferation of membrane material, designated as virocytonecrosis.
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