Key result
Hypertension is linked to ~55% higher plasma urotensin II levels versus normotensive controls.
Why the study?
Are plasma urotensin II levels elevated in hypertensive patients compared to normotensive controls?
Population
124 human subjects, comprising 62 hypertensive outpatients and 62 normotensive controls recruited from the…
Design
Case-control
Authors
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May suggest etiological role in hypertension; leaves open causal inference and clinical utility.
Case-Control (n=124)
No
Are plasma urotensin II levels elevated in hypertensive patients compared to normotensive controls?
Absolute Event Rate: 13.6% vs 8.8%
p-value: p=0.005
Plasma urotensin II levels are elevated in hypertensive patients and correlate with systolic blood pressure, suggesting a potential etiological role in hypertension.
Cheung et al. (2004) conducted a case-control in Hypertension (n=124). Hypertension vs. Normotensive controls was evaluated on Plasma urotensin II levels (p=0.005). Plasma urotensin II levels were significantly higher in hypertensive patients (13.6 pmol/l) compared to normotensive controls (8.8 pmol/l; P=0.005).
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