Key result
Exercise recommendations for Marfan syndrome and genetic thoracic aortic disease lack supporting outcomes studies.
Why the study?
What are the appropriate exercise recommendations for patients with Marfan syndrome or inherited aortopathies?
What are the appropriate exercise recommendations for patients with Marfan syndrome or inherited aortopathies?
This review highlights the lack of outcomes data and the reliance on theoretical reasoning for current exercise guidelines in patients with inherited aortopathies.
Exercise recommendations for Marfan syndrome and inherited aortopathies lack outcomes data; leaves open whether current restrictions alter prognosis.
Exercise recommendations for those who have Marfan syndrome or other genetic predisposition for thoracic aortic disease remain controversial and at times ambiguous. There are no outcomes studies to help guide recommendations. In this review, we examine the guidelines regarding exercise and inherited aortic conditions, the theoretical reasoning and circumstantial evidence that support the guidelines, as well as the knowledge gaps that continue to exist.
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Cheng et al. (2015) conducted a review in Marfan syndrome or other genetic predisposition for thoracic aortic disease. Exercise was evaluated. There are currently no outcomes studies to help guide exercise recommendations for patients with Marfan syndrome or other genetic predispositions for thoracic aortic disease.
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