Key result
Exercise recommendations for Marfan syndrome and inherited aortopathies lack supporting outcomes data.
Why the study?
What are the appropriate exercise recommendations for individuals with Marfan syndrome or inherited aortopathies?
What are the appropriate exercise recommendations for individuals with Marfan syndrome or inherited aortopathies?
Exercise recommendations for Marfan syndrome and inherited aortopathies remain controversial and rely on theoretical reasoning rather than clinical outcomes data.
Exercise recommendations for Marfan syndrome and aortopathies warrant ongoing caution without outcomes data; leaves open the need for prospective trials to inform guidelines.
Exercise recommendations for those who have Marfan syndrome or other genetic predisposition for thoracic aortic disease remain controversial and at times ambiguous. There are no outcomes studies to help guide recommendations. In this review, we examine the guidelines regarding exercise and inherited aortic conditions, the theoretical reasoning and circumstantial evidence that support the guidelines, as well as the knowledge gaps that continue to exist.
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Cheng et al. (2015) conducted a review in Marfan syndrome and inherited aortopathies. Exercise was evaluated. This review highlights the lack of outcomes studies to guide exercise recommendations for patients with Marfan syndrome and inherited aortopathies, examining current guidelines and knowledge gaps.
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