Key result
Nunez aortic root enlargement linked to reduced or eliminated patient-prosthesis mismatch in ~94% of patients.
Why the study?
Does aortic root enlargement using the Nunez procedure improve hemodynamics and reduce patient-prosthesis mismatch in patients undergoing aortic valve replacement with small aortic roots?
Observational (n=17)
Does aortic root enlargement using the Nunez procedure improve hemodynamics and reduce patient-prosthesis mismatch in patients undergoing aortic valve replacement with small aortic roots?
Aortic root enlargement using the Nunez procedure safely allows for the implantation of larger aortic valve prostheses, improving hemodynamics and reducing patient-prosthesis mismatch.
BACKGROUND: The choice of a valve with an effective orifice area matching the body surface area and providing efficient hemodynamics is an important factor affecting mortality and morbidity in patients undergoing aortic valve replacement. PATIENTS AND METHODS: Our preventative strategy was to implant a larger prosthetic valve by aortic root enlargement using the Nunez procedure in 17 patients between February 2010 and January 2011. The decision to enlarge the aortic root was taken when the 19-mm sizer could not be negotiated easily through the aortic root, or on the basis of body surface area of the patient or type of prosthesis available. RESULTS: Postoperative reductions in peak and mean pressure gradients across aortic valve of 12.8-16.5 and 10.2-12.6 mm Hg, respectively, were observed. Postoperative effective orifice areas of the aortic valves were 1.1-1.5 cm(2). By upsizing the aortic valve, we were able to eliminate patient-prosthesis mismatch in 5 patients, and reduce severe patient-prosthesis mismatch to moderate in 11. CONCLUSION: Aortic root enlargement is a safe procedure. Therefore, cardiac surgeons should not be reluctant to enlarge the aortic root with an autologous pericardial patch to permit implantation of an adequate size of aortic valve prosthesis, with minimal additional aortic crossclamp time and no added cost.
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Srivastava et al. (2013) conducted an observational in Aortic valve replacement with risk of patient-prosthesis mismatch (n=17). Aortic root enlargement using the Nunez procedure was evaluated on Postoperative reductions in peak and mean pressure gradients and effective orifice areas. Aortic root enlargement using the Nunez procedure eliminated patient-prosthesis mismatch in 5 of 17 patients and reduced severe mismatch to moderate in 11 patients.
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