Severe calcification does not affect long-term outcome of mitral valve repair
Key result
Calcium debridement in mitral valve repair fails to improve 10-year freedom from reoperation versus nondebridement.
- P not significant
- n=558
Why the study?
Does calcium debridement during mitral valve repair affect the long-term risk of reoperation in patients with calcified mitral valves?
Population
558 patients undergoing mitral valve repair using Carpentier's techniques from June 1979 through June 1993…
Comparison
Mitral valve repair with calcium debridement vs Mitral valve repair without calcium debridement
Design
Cohort
Follow-up
10 years
Authors
Discussion
Loading...
Member takes
Implication
May support debridement in calcified mitral valves; leaves open need for randomized confirmation of durability.
Study Design
Type
Cohort (n=558)
Multicenter
No
Structured PICO
Does calcium debridement during mitral valve repair affect the long-term risk of reoperation in patients with calcified mitral valves?
P
Population
558 patients (mean age 62.3 years) undergoing mitral valve repair, including 64 requiring calcium debridement, followed for up to 10 years.
E
Exposure
Mitral valve repair with calcium debridement (annular debridement and/or mechanical leaflet decalcification)
C
Comparator
Mitral valve repair without calcium debridement
O
Outcome
Cumulative freedom from reoperation at 10 yearshard clinical
Main Result
Absolute Event Rate: 88.1% vs 82.6%
p-value: p=not significant
Calcium debridement during mitral valve repair in patients with severe calcification allows for durable repairs with long-term freedom from reoperation comparable to non-calcified valves.
Cite This Study
Grossi et al. (1994) conducted a cohort in Mitral valve disease with severe calcification (n=558). Calcium debridement vs. No debridement was evaluated on Cumulative freedom from reoperation at 10 years (p=not significant). Calcium debridement during mitral valve repair yielded a 10-year freedom from reoperation of 88.1%, comparable to 82.6% in nondebrided patients (p=not significant).