Key result
EVAR since 2012 is linked to ~67% fewer late open conversions versus the 1997-2011 era.
Why the study?
Does the time period of EVAR (2012-2020 vs 1997-2011) reduce the incidence of late open conversion in patients with infrarenal aortic aneurysm?
Cohort (n=749)
No
Does the time period of EVAR (2012-2020 vs 1997-2011) reduce the incidence of late open conversion in patients with infrarenal aortic aneurysm?
Absolute Event Rate: 1.7% vs 5.2%
Technical progress and adherence to instructions for use have significantly reduced the incidence of late open conversion after EVAR.
Late open conversion after EVAR warrants vigilant follow-up; retrospective data leaves open whether complication rates have changed over time.
Late open conversion in our center has been reviewed in the past 8 years, comparing 1997-2011 (first period group A) with 2012-2020 (second period group B). A retrospective analysis of patients treated at our centre by standard EVAR for infrarenal aortic aneurysm requiring late open conversion between January 1997 and February 2020 was performed. All stent grafts were implanted according to their current IFU all patients. The data concerning intra and postoperative complications were collected. Post-operative evaluated data include: ICU (Intensive Care Unit) stay, major peri-operative (<30 days) complications, in hospital mortality, length of hospital stay, 30-days mortality, and mid-term outcomes. Between January 2012 and February 2020 (group B), in our institution 8 patients previously treated by stent graft with endoleak underwent open surgery. The incidence of conversions and the 30-day mortality rate were compared with that of previous years, from January 1997 to December 2011 (group A). 481 patients submitted to EVAR in a second part of the analysis have been considered, 8 patients underwent late open conversion (1.7%) (Group B) due to endoleak. Among January 1997 and December 2011 overall 268 EVAR were performed; during this first study period, surgical conversion had been performed in 14 patients (5.2%) (Group A). The average time from EVAR to open conversion was four years (range 12-88 months) in Group B, and it was 30 months (range 1-82 months) in Group A. In most cases, in both group A and group B the proximal aortic cross-clamping were infrarenal. After the emergent procedure in Group B (12.5%), we have observed a death, whereas three patients died in Group A in urgent situations (21.4%). The more frequent indication for open surgery is the Endoleak type 1 and migration in the two considered periods. Adherence with current IFU and the technical progress in endoprosthesis design maintain lower rate incidence. In most cases, open surgery for prostheses that require explantation can be performed with infrarenal clamping. Partial removal of the endoprosthesis in selected cases makes open conversion easier and appears durable. The results are unfair by numerous comorbidities; in both periods, urgent graft removal seems to elevate both mortality and morbidity, compared to elective surgery.
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Marchetti et al. (2021) conducted a cohort in Infrarenal aortic aneurysm (n=749). EVAR performed between 2012-2020 vs. EVAR performed between 1997-2011 was evaluated on Incidence of late open conversion. The incidence of late open conversion after EVAR decreased from 5.2% in the 1997-2011 period to 1.7% in the 2012-2020 period.
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