Key result
PCOS is linked to ~150% higher insulin resistance versus healthy controls.
Why the study?
The study was conducted to find out the level of insulin and insulin resistance in polycystic ovary syndrome.
Are insulin and insulin resistance levels altered in women with polycystic ovary syndrome compared to controls?
Population
30 Polycystic Ovarian Syndrome female patients aged 15-40 years
Comparison
Polycystic ovary syndrome patients vs controls
Authors
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May warrant metabolic screening in PCOS; extends case-control data but leaves causal CV implications open.
Case-Control (n=55)
No
Are insulin and insulin resistance levels altered in women with polycystic ovary syndrome compared to controls?
Absolute Event Rate: 8.102% vs 3.205%
p-value: p=0.0001
Insulin and insulin resistance are significantly altered in PCOS patients, highlighting the importance of routine metabolic screening to mitigate the risk of developing diabetes and cardiovascular diseases.
Sonagara et al. (2020) conducted a case-control in Polycystic Ovary Syndrome (n=55). Polycystic Ovary Syndrome vs. Healthy controls was evaluated on Insulin Resistance (p=0.0001). Polycystic ovary syndrome was associated with significantly higher insulin resistance compared to healthy controls (8.102 vs 3.205, p=0.0001).
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