Key result
PCOS is linked to ~150% higher insulin resistance versus healthy controls.
Why the study?
The study was conducted to find out the level of insulin and insulin resistance in polycystic ovary syndrome.
Are insulin and insulin resistance levels altered in women with polycystic ovary syndrome compared to controls?
Case-Control (n=55)
No
Are insulin and insulin resistance levels altered in women with polycystic ovary syndrome compared to controls?
Answers are grounded in this paper and cite their sources.
Insulin and insulin resistance are significantly altered in PCOS patients, highlighting the importance of routine metabolic screening to mitigate the risk of developing diabetes and cardiovascular diseases.
Introduction: To find out the level of insulin and insulin resistance in polycystic ovary syndrome. Material and methods: The present study was conducted on 30 Polycystic Ovarian Syndrome female patients of age group (15-20, 20-30 and 30-40years) attending the Out Patient Clinics of Department of Obstetrics and Gynaecology, Dr. S.N. Medical College and its associated group of Hospitals, Jodhpur. Glucose, insulin and insulin resistance biochemical parameters were analyzed by commercially available reagents and kits using semi auto and fully auto analyzers. Results: we have found a very significant and statically significant change in insulin and insulin resistance in polycystic ovary syndrome in comparison to controls . Conclusion: Regular evaluation of Blood Sugar, Insulin, Insulin Resistance routinely in PCOS patients that may have utility of complication, risk prediction and diagnostic role in the early detection of metabolic abnormalities, endocrine derangements and active and timely management of these alterations can prevent the risk squeal of co-morbid conditions of development of Diabetes and Cardiovascular diseases in Polycystic Ovarian Syndrome females.
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Sonagara et al. (2020) conducted a case-control in Polycystic Ovary Syndrome (n=55). Polycystic Ovary Syndrome vs. Healthy controls was evaluated on Insulin Resistance (p=0.0001). Polycystic ovary syndrome was associated with higher insulin resistance compared to healthy controls.
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