Key result
IV tPA for acute ischemic stroke is linked to fatal acute MI in 2 patients.
Case Report (n=2)
Acute myocardial infarction is a rare but serious and potentially fatal complication immediately following IV tPA administration for acute ischemic stroke, possibly due to disruption and embolization of intracardiac thrombus.
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Fatal MI may follow IV tPA for stroke; case reports leave open incidence and causality.
Adatia et al. (2010) conducted a case report in Acute ischemic stroke (n=2). Intravenous tissue plasminogen activator (tPA) was evaluated on Acute myocardial infarction. Intravenous tissue plasminogen activator administration for acute ischemic stroke was followed by fatal acute myocardial infarction in 2 patients.
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