Key result
Depression worsens HF prognosis, while antidepressants show controversial efficacy compared to CBT and exercise.
Why the study?
Depression in heart failure is common, associated with adverse outcomes, and underdiagnosed, with specific screening guidelines lacking.
Depression is common and underdiagnosed in heart failure patients, contributing to adverse outcomes, though cognitive-behavioral therapy and SSRIs offer potential management strategies.
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Routine depression screening merits consideration in HF; leaves open optimal therapy given controversial antidepressant evidence.
Aloisi et al. (2019) conducted a review in Heart failure and depression. Depression screening and management was evaluated. Depression affects 11-51% of heart failure patients and worsens prognosis, while evidence for the efficacy of antidepressants remains controversial compared to cognitive behavioral therapy and exercise.
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