Key result
High-speed 1000-fps stereo imaging successfully identifies spreading left ventricular ischemia in a rat MI model.
High-speed stereo video imaging with surface markers can quantitatively evaluate spatiotemporal changes in cardiac motion and infarct spread in a rat model of myocardial infarction.
High-speed stereo imaging quantifies regional myocardial dynamics in rat MI models; leaves open translation to clinical cardiac imaging.
In this study, we performed a cardiac motion analysis by using 1000-frames per second (fps) stereo images to capture the three-dimensional motion of small color markers in a rat heart. This method of recording cardiac motion could quantify the rate of change in the myocardial area, which indicated localized myocardial activity of rhythmic expansion and contraction. We analyzed the three-dimensional motion distributions in a rat model for myocardial infarction, in which the heart rate was 4 times/s or more. In the analysis, we spatiotemporally quantified the characteristic cardiac motion in ischemic heart diseases and found that infarction due to ischemia in the rat heart was spread around the left ventricle.
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Ishii et al. (2010) studied Myocardial infarction (rat model). High-speed video (1000 fps) stereo imaging was evaluated on Spatiotemporal quantification of cardiac motion (rate of change in myocardial area). High-speed 1000-fps stereo imaging successfully quantified the rate of change in myocardial area, identifying localized ischemic regions spreading around the left ventricle in a rat model of myocardial infarction.
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