Key result
Thorax radiographs establish baseline VHS and CTR reference values in normal male Wistar rats.
Why the study?
The study was conducted to determine and compare vertebral heart size and cardio-thoracic rate in normal Wistar rats, as no previous reference values existed.
Observational (n=85)
p-value: p=0.3530
This study establishes reference values for Vertebral Heart Size and Cardio-Thoracic Rate in normal Wistar rats using digital thorax radiographs.
Normative VHS/CTR values in healthy Wistar rats; leaves open validation and utility in disease models or other strains.
The purpose of this study was to determine and compare the Vertebral Heart Size (VHS) and Cardio-Thoracic Rate (CTR) in normal Wistar Rats. The size of the organs in the chest cavity and the size of the heart can be measured by taking thorax radiographs. Thorax radiographs of 85 male Wistar rats were taken under anesthesia, and VHS and CTR were calculated in the digital environment. The mean VHS was 7.22 mm in the right lateral position and 7.34 mm in the left lateral position. In the radiography taken in the ventrodorsal position (P = 0.3530), the mean CTR was calculated as 0.89 mm. Also, no significant correlation was measured between VHS and CTR. In conclusion, our study results can be reference values, as no previous study has been found for Wistar rats.
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Doğan et al. (2021) conducted an observational in Normal Wistar rats (n=85). Thorax radiographs was evaluated on Vertebral Heart Size (VHS) and Cardio-Thoracic Rate (CTR) (p=0.3530). Thorax radiographs in 85 normal male Wistar rats established reference values of 7.22 mm and 7.34 mm for right and left lateral Vertebral Heart Size, and 0.89 mm for Cardio-Thoracic Rate.
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