Why the study?
Does high-frequency echocardiography accurately measure left ventricular mass in normal and hypertrophied rat models compared to direct anatomic measurement?
Population
65 male rats, aged 5 to 30 weeks, weighing 105 to 705 grams.
Comparison
High-frequency two-dimensional and M-mode… vs Direct anatomic measurement of left ventricular…
Design
Preclinical
Authors
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Supports non-invasive LV mass tracking in rodent models; leaves open clinical translation.
Does high-frequency echocardiography accurately measure left ventricular mass in normal and hypertrophied rat models compared to direct anatomic measurement?
High-frequency echocardiography provides an accurate and highly reproducible non-invasive method for determining left ventricular mass in normal and hypertrophied rat models.
Nakamura et al. (1991) studied this question.
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