Why the study?
Does echocardiography provide an accurate and repeatable estimate of left ventricular mass in rats compared to direct measurement?
Population
Male rats, including spontaneously hypertensive rats (SHR) and normotensive Donryu rats (DRY)
Comparison
Non-invasive echocardiographic methods for… vs Direct measurement of left ventricular weight at…
Design
Preclinical
Authors
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Supports non-invasive LVM assessment in rat hypertrophy models; leaves open human validation before clinical use.
Does echocardiography provide an accurate and repeatable estimate of left ventricular mass in rats compared to direct measurement?
Echocardiography provides a repeatable and relatively accurate non-invasive method for estimating left ventricular mass in rat models of cardiac hypertrophy.
Jones et al. (1992) studied this question.
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