Key result
Multistix PRO IOLS correlates well with quantitative P/C ratios to predict 24-hour urine protein.
Why the study?
Does the Multistix PRO IOLS test paper accurately predict 24-hour urinary protein excretion using random urine samples in patients with renal diseases?
Observational (n=235)
No
Does the Multistix PRO IOLS test paper accurately predict 24-hour urinary protein excretion using random urine samples in patients with renal diseases?
The Multistix PRO IOLS test paper using random urine samples can reliably predict 24-hour urinary protein excretion in patients with renal diseases.
Answers are grounded in this paper and cite their sources.
May support dipstick PCR for spot urine proteinuria estimates in renal disease; leaves open prospective validation before practice change.
We assessed the new test paper Multistix PRO IOLS, in which the +/-region of the conventional test for protein was altered so that creatinine correction became possible. Urinary samples from 235 patients with various renal diseases were obtained from the Juntendo University Hospital. We examined 1) the correlation between qualitatively measured values of urinary protein by the new test paper and the conventional test paper, and 2) the correlation between qualitative and quantitative values of protein (P), creatinine (C), and the P/C ratio measured by the new test paper. There was a good correlation between the P/C ratio observed with the new test paper and that observed by quantitative analysis. There was also a good correlation of the P/C ratio between 24-hr urine and urinary samples obtained at any time of day. Thus, it appears that the results obtained from urinary samples any time of day can predict the amount of protein excreted during the day.
No takes yet. Share an insight, caveat, or question.
Watanabe et al. (2005) conducted an observational in renal diseases (n=235). Multistix PRO IOLS test paper vs. conventional test paper and quantitative analysis was evaluated on correlation between P/C ratio observed with the new test paper and quantitative analysis. The Multistix PRO IOLS test paper showed good correlation with quantitative analysis for protein/creatinine ratios in random urine samples, predicting 24-hour protein excretion.
Synapse has enriched 10 related papers. Consider them for comparative context: