Key result
The urinary protein-osmolality ratio strongly correlated with 24-hour protein levels (r = 0.88) and was better than the urinary protein-creatinine ratio for assessing abnormal proteinuria.
Why the study?
Does the urinary protein-osmolality ratio accurately predict 24-hour urine protein levels in normal and proteinuric patients?
Population
78 normal women, 53 normal men, and 129 proteinuric patients; 131 normal patients and 105 proteinuric patients
Comparison
Urinary protein-osmolality ratio from a random… vs 24-hour urine protein level and urinary…
Design
Cross-sectional
Authors
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The quantitative urinary protein-osmolality ratio from a random sample is a highly sensitive and specific predictor of 24-hour protein levels, outperforming qualitative urinalysis and protein-creatinine ratios.
Cross-Sectional (n=260)
Does the urinary protein-osmolality ratio accurately predict 24-hour urine protein levels in normal and proteinuric patients?
Effect estimate: r = 0.88
The quantitative urinary protein-osmolality ratio from a random sample is a highly sensitive and specific predictor of 24-hour protein levels, outperforming qualitative urinalysis and protein-creatinine ratios.
Wilson et al. (1993) conducted a cross-sectional in Proteinuria (n=260). Urinary protein-osmolality ratio vs. Urinary protein-creatinine ratio and 24-hour urine protein was evaluated on Prediction of 24-hour urine protein level (r = 0.88). The urinary protein-osmolality ratio strongly correlated with 24-hour protein levels (r = 0.88) and was better than the urinary protein-creatinine ratio for assessing abnormal proteinuria.
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