Key result
CT-guided TAV-in-SAV with an Evolut FX valve successfully avoids sinus sequestration in an at-risk patient.
Why the study?
Sinus sequestration may occur in transcatheter aortic valve (TAV)-in-surgical aortic valve (SAV), and its risk may be underrecognized if not assessed properly.
Case Report (n=1)
Detailed preprocedural CT planning, including maximum intensity projection images, is crucial for identifying and mitigating the risk of sinus sequestration during TAV-in-SAV procedures.
Supports detailed CT planning in high-risk TAV-in-SAV; leaves open generalizability pending larger prospective data.
BACKGROUND: Sinus sequestration, well discussed in transcatheter aortic valve (TAV)-in-TAV, may also occur in TAV-in-surgical aortic valve (SAV), and its risk may be underrecognized if not assessed properly. We report an optimized TAV-in-SAV procedure in a patient at risk for sinus sequestration who was successfully treated after detailed computed tomography (CT) planning. CASE SUMMARY: An 85-year-old woman who underwent previous surgical aortic valve replacement (Magna #19 valve, Edwards Lifesciences) presented with severe bioprosthetic stenosis. A TAV-in-SAV procedure was planned using an Evolut FX 23-mm valve (Medtronic) with optimization using a 20-mm balloon, which corresponds to the in vitro waist diameter of the Evolut FX 23-mm valve. Preprocedural CT, including maximum intensity projection (MIP) images, indicated a risk for sinus sequestration. A thorough CT assessment performed on the basis of this plan led to a successful optimized procedure. DISCUSSION: Identifying sinus sequestration risk is crucial in TAV-in-SAV. MIP images on CT may help visualize the relationship between the neoskirt and the sinotubular junction. Optimizing TAV expansion is essential, and CT assessment should be conducted on the basis of the planned procedure.
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Irie et al. (2025) conducted a case report in Severe bioprosthetic stenosis (n=1). TAV-in-SAV procedure with CT planning was evaluated on Successful optimized procedure avoiding sinus sequestration. A TAV-in-SAV procedure using an Evolut FX 23-mm valve was successfully performed in an 85-year-old woman at risk for sinus sequestration following detailed computed tomography planning.
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