Key result
Accidental single-dose aripiprazole ingestion linked to severe EPS in a 3-year-old boy.
Why the study?
Does accidental ingestion of aripiprazole cause severe extrapyramidal symptoms in a 3-year-old boy?
Case Report (n=1)
Does accidental ingestion of aripiprazole cause severe extrapyramidal symptoms in a 3-year-old boy?
Accidental ingestion of aripiprazole in young children can lead to severe extrapyramidal symptoms.
Accidental aripiprazole ingestion may cause severe extrapyramidal symptoms in toddlers; leaves open incidence and management.
To the Editor .— Aripiprazole is a new type of antipsychotic medication exhibiting high-affinity partial agonist activity at D2-dopamine receptors.1,2 When used in adults for the treatment of schizophrenia and schizoaffective disorder, aripiprazole has been associated with extrapyramidal symptoms (EPS) at a rate similar to that of placebo.3 Although it has been used in children, aripiprazole's safety profile in pediatric age groups is unknown.2,4 We report a case of severe EPS in a 3-year-old boy after accidental ingestion of a single dose of <15 …
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Schonberger et al. (2004) conducted a case report in Accidental ingestion of aripiprazole (n=1). Aripiprazole was evaluated on Extrapyramidal symptoms (EPS). Accidental ingestion of a single dose of aripiprazole resulted in severe extrapyramidal symptoms in a 3-year-old boy.
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