Key result
Aortic valve sclerosis shows no independent link to coronary artery disease severity or complexity.
Why the study?
Does the presence of aortic valve sclerosis predict the severity and complexity of coronary artery disease?
Observational (n=482)
Does the presence of aortic valve sclerosis predict the severity and complexity of coronary artery disease?
Aortic valve sclerosis appears to be a benign marker of age-related degenerative changes rather than an independent predictor of coronary artery disease severity or complexity.
AVS should not guide CAD risk stratification in practice; leaves open its value as an atherosclerosis marker beyond age in prospective cohorts.
AIM: We assessed the association of aortic valve sclerosis (AVS) with atherosclerotic risk factors and severity and complexity of coronary artery disease (CAD). METHODS: In this retrospective study, a total of 482 eligible patients were divided into 2 groups: AVS present and AVS absent. All major cardiovascular risk factors and coronary lesion characteristics were included. RESULTS: Age was the only independent predictor of AVS. AVS was not independently associated with the number of obstructive vessels, degree of lesion obstruction and SYNTAX score. CONCLUSION: AVS is probably a benign marker of age-related degenerative changes in the heart independent of the severity and complexity of CAD.
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Bhatt et al. (2015) conducted an observational in Coronary artery disease (n=482). Aortic valve sclerosis vs. Absence of aortic valve sclerosis was evaluated on Severity and complexity of coronary artery disease (number of obstructive vessels, degree of lesion obstruction and SYNTAX score). Aortic valve sclerosis was not independently associated with the severity and complexity of coronary artery disease, including the number of obstructive vessels, degree of obstruction, and SYNTAX score.
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