Why the study?
Primary synovial sarcoma of the pleura is a rare disease, and cases presenting with two tumors had not been previously reported.
Case Report (n=1)
No
This case report highlights the successful treatment of a rare primary synovial sarcoma of the pleura presenting with two tumors using surgery and chemotherapy.
Supports multimodal therapy for rare pleural synovial sarcoma; hypothesis-generating and should not yet change practice.
Primary synovial sarcoma of the pleura (PSSP) is a rare disease. The present study reported the case of a patient (male; age, 18 years) with two tumors (7.8×2.8 cm and 6.5×5.8 cm) treated with surgery and chemotherapy. To the best of our knowledge, this is the first reported case of two tumors diagnosed as PSSP, which was confirmed by immunohistochemical staining. After six months of follow-up, the symptoms of dry cough and wheezing disappeared and all of the laboratory results were within normal limits. PSSP requires clinical suspicion combined with strategic diagnostic evaluation to confirm the diagnosis and a comprehensive treatment program based on surgery and assisted by chemotherapy.
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Zang et al. (2023) conducted a case report in Primary synovial sarcoma of the pleura (n=1). Surgery and chemotherapy (ifosfamide and doxorubicin) was evaluated on Symptom resolution and tumor recurrence/metastasis.
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