Key result
Isolated U-wave inversion may portend acute MI hours before typical ECG changes.
Why the study?
Does isolated U-wave inversion portend an acute myocardial infarction?
Case Report (n=3)
Does isolated U-wave inversion portend an acute myocardial infarction?
Isolated U-wave inversion in the appropriate clinical context may be an early electrocardiographic sign portending acute myocardial infarction.
May signal impending MI in select cases; leaves open its diagnostic utility pending prospective validation.
Three patients are presented in whom an isolated inversion of the U wave preceded by several hours typical electrocardiographic changes of an acute myocardial infarction. The association of transient hypertension and an acute U-wave inversion during this period of myocardial ischemia is discussed. It is suggested that within the appropriate clinical context an isolated U-wave inversion may portend an acute myocardial infarction.
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Martin Duke (2008) conducted a case report in Acute Myocardial Infarction (n=3). Isolated U-wave inversion was evaluated on Acute myocardial infarction. Isolated U-wave inversion preceded typical electrocardiographic changes of acute myocardial infarction by several hours in three patients, suggesting it may portend an acute MI.
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