Key result
Early surgery, complete resection, and chemotherapy linked to improved survival in primary cardiac tumors.
Why the study?
Primary cardiac tumors are rare and malignant forms carry a dismal prognosis without early diagnosis and surgical resection followed by adjuvant therapy.
Does early surgery, complete resection, and chemotherapy enhance survival in patients with primary cardiac tumors?
Cohort (n=60)
No
Does early surgery, complete resection, and chemotherapy enhance survival in patients with primary cardiac tumors?
Early surgery, complete resection, and adjuvant chemotherapy are suggested to enhance survival in patients with rare primary cardiac tumors.
Early diagnosis and multimodal therapy may improve outcomes in young cardiac sarcoma patients; leaves open optimal protocols for these rare tumors.
Primary cardiac tumors are rare. The incidence varies between 0.3% to 0.7% .Quarter of all primary cardiac tumors are malignant, of these 75% are sarcomas. Malignant primary cardiac sarcomas that affect right atrium are predominantly angiosarcomas while the left atrium is involved primary in pleomorphic sarcoma like malignant brous histiocytoma and leiomyosarcoma. In a young patient it usually carries a dismal prognosis if not diagnosed early and dealt with surgically followed by adjuvant therapy. Without surgical resection, the survival rate at 1yr is only 10%.Retrospective evaluation of the last 60 primary cardiac tumors done by the same surgical team over 28 years was looked into.
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Radhakrishnan et al. (2021) conducted a cohort in Primary cardiac tumors (n=60). Early surgery, complete resection, and chemotherapy was evaluated. Early surgery, complete resection, and chemotherapy enhance survival in patients with primary cardiac tumors.
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