This review highlights the clinical presentation of cobalt-induced cardiomyopathy, historically known as Quebec beer drinkers' cardiomyopathy, which was associated with a 42% early mortality rate.
Rat cobalt exposure models confirm myocardial ultrastructure injury; leaves open relevance to contemporary human cobalt cardiomyopathy surveillance.
Introduction “Quebec beer drinkers’ cardiomyopathy” appeared as an epidemic among heavy beer drinkers in Canada in the mid-1960’s [1]. The cardiomyopathy resembled typical dilated cardiomyopathy, except for purplish skin coloration and a high early mortality rate (42%). It was associated with development of a large pericardial effusion and low output heart failure. Quebec beer
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Zadnipryany et al. (2017) studied Cobalt-induced cardiomyopathy (n=15). Cobalt chloride was evaluated on Structural changes of myocardial cells and interstitial connective tissue.
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