Coronary artery volume to left ventricular myocardial mass ratio in detecting primary microvascular angina: a retrospective observational study in Chinese population

Figures

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  Fig. 1. Workflow diagram of this study. CCTA: coronary computed tomography (CT) angiography, PMVA: primary microvascular angina, V/M: the ratio of coronary artery volume to left ventricular myocardial mass, CT-FFR: CT-derived fractional flow reserve

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  Fig. 2. Patient screening and matching process

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  Fig. 3. Schematic diagram of V/M calculation method. CCTA: coronary computed tomography (CT) angiography, V/M: the ratio of coronary artery volume to left ventricular myocardial mass

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  Fig. 4. Standardized myocardial segmentation proposed by American Heart Association

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  Fig. 5. Correlation analysis of FFR and IMR

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  Fig. 6. Comparison of coronary artery lumen volume (V), myocardial mass (M), and V/M ratio between the PMVA and control groups. A Distribution of coronary artery lumen volume in two groups. B Distribution of myocardial mass in two groups. C Distribution of V/M ratio in two groups. The internal boxplots depict the median and quartiles, with the bold horizontal line representing the median, and the upper and lower bounds corresponding to the upper and lower quartiles. The three long horizontal lines represent the mean ± standard deviation. “ns” indicates non-significant difference, “*” and “**” indicates significant differences (P < 0.05 and P < 0.01). PMVA: primary microvascular angina

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  Fig. 7. Receiver operating characteristic (ROC) curve of patient-specific V/M. AUC: area under curve

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  Fig. 8. Comparison of the vessel-specific V/M values in left anterior descending artery (LAD), left circumflex artery (LCX), and right coronary artery (RCA) between PMVA and control groups. The internal boxplots depict the median and quartiles, with the bold horizontal line representing the median, and the upper and lower bounds corresponding to the upper and lower quartiles. The three long horizontal lines represent the mean ± standard deviation. “ns” indicates non-significant difference, “*” indicates significant differences (P < 0.05)