Why the study?
Prognostic indicators in patients with inflammatory cardiomyopathy on endomyocardial biopsy needed to be identified.
Cohort
BACKGROUND: The objective of this study was to identify prognostic indicators in patients with inflammatory cardiomyopathy (iCM) on endomyocardial biopsy (EMB). METHODS AND RESULTS: = 40) reached the primary endpoint. Independent predictors for the 1°EP were: age ≥ 50 years, presence and duration (≤ 28 days) of symptomatic heart failure. A risk stratification approach based on the results of the multivariate analysis demonstrated that absence of signs and/or symptoms of congestive heart failure in younger (< 50 years) patients with longer (> 28 days) duration of disease appear to have an excellent prognosis with 100% survival and no events during follow-up. The presence of all above mentioned independent risk factors results in an 1°EP occurrence of 35.9%. CONCLUSIONS: Symptoms of heart failure, short duration of disease, and older age are indicators of poor outcome in patients with iCM.
No takes yet. Share an insight, caveat, or question.
Ohlow et al. (2018) conducted a cohort in Inflammatory cardiomyopathy (iCM). Age ≥ 50 years, symptomatic heart failure, and disease duration ≤ 28 days vs. Absence of these risk factors was evaluated on Primary endpoint (not explicitly defined, includes survival/events).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: