Design
Review
Key result
Oxidative stress plays a major role in cardiovascular disease by causing endothelial dysfunction, with the adventitia and NAD(P)H oxidase acting as important sources of reactive oxygen species.
Authors
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Challenges precise targeting of oxidative stress in specific CVD; leaves open endothelial mechanisms for targeted trials.
This symposium summary highlights the central role of oxidative stress and endothelial dysfunction in cardiovascular disease, emphasizing mechanisms involving NO, ADMA, and environmental factors like pollution.
R. M. Wadsworth (2007) conducted a review in Cardiovascular disease. Oxidative stress was evaluated. Oxidative stress plays a major role in cardiovascular disease by causing endothelial dysfunction, with the adventitia and NAD(P)H oxidase acting as important sources of reactive oxygen species.
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