Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
December 8, 2012Journal of Cardiovascular Pharmacology

The review highlights the interplay between the renin-angiotensin system, nicotinamide adenine dinucleotide phosphate, reduced oxidase, bone morphogenic protein 4, and cyclooxygenase 2-derived prostaglandins as a concerted pathogenic cascade in inducing and maintaining endothelial dysfunction in hypertension and diabetes.

View Full Paper
Ask AI
Bookmark
Share

Design

Review

Authors

WWWing Tak WongXTXiao Yu TianYHYü Huang

Discussion

Loading...

Member takes

Overview

Does not change clinical practice in hypertension or diabetes; extends mechanistic insights into endothelial dysfunction for future research.

Key Points

Key points are not available for this paper at this time.

Cite This Study

Wong et al. (2012) studied this question.

synapsesocial.com/papers/6a76b7fad8eb58afc2bd5b00https://doi.org/10.1097/fjc.0b013e31827fe46e
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Endothelial Dysfunction: The Common Consequence in Diabetes and Hypertension2010 · 133 citations
  2. 2Endothelial Dysfunction in Diabetes – Clasic Sources of Vascular Oxidative Stress (Nadph Oxidases, Enos Uncoupling and Xanthine Oxidase)2013 · 1 citations
  3. 3Endothelial dysfunction in diabetes2000 · 1,168 citations
  4. 4Endothelial dysfunction in cardiovascular and endocrine-metabolic diseases: an update2011 · 88 citations
  5. 5Possible Involvement of Insulin and Oxidative Stress in Vascular Dysfunction of Diabetic Mellitus2008 · 9 citations