Key result
TEE-derived P-LAA correlates strongly with invasive measurement of interatrial conduction time.
Why the study?
Recurrence of atrial fibrillation is more common in patients with atrial conduction delay, and correlation between noninvasive and invasive methods to measure interatrial conduction time was evaluated.
Does the P-LAA interval measured by TEE correlate with invasive interatrial conduction time measured by EPS?
Cross-Sectional (n=33)
Does the P-LAA interval measured by TEE correlate with invasive interatrial conduction time measured by EPS?
Effect estimate: r = 0.839
Absolute Event Rate: 49.91% vs 46.27%
p-value: p=< 0.0001
The P-LAA interval measured by TEE provides a reliable, relatively noninvasive estimate of interatrial conduction time, which may be useful in predicting atrial fibrillation recurrence.
Atrial conduction delay may signal higher AF recurrence risk; leaves open whether TEE reliably surrogates EPS in larger cohorts.
UNLABELLED: Recurrence of atrial fibrillation is more common in patients with atrial conduction delay. In the present study, we evaluated whether findings obtained from transesophageal echocardiography (TEE), a semi-invasive method, correlate with those from an invasive method, electrophysiologic study (EPS), in measuring interatrial conduction time. METHODS AND RESULTS: We compared two methods of calculating interatrial conduction time in a group of 33 patients. The origin of the P-wave on the surface electrocardiogram (ECG) was taken as the onset of atrial activation. The time interval from this point to the commencement of the left atrial appendage ejection flow (P-LAA) was measured by TEE. Meanwhile, simultaneous recordings of the left atrial appendage were obtained with a catheter positioned in the LAA, and an invasive interatrial conduction time was measured from the origin of the surface's earliest P-wave (I-IACT). The mean I-IACT (46.27 +/- 13.25 ms) correlated strongly with the mean P-LAA (49.91 +/- 12.72 ms; r = 0.839, P < 0.0001). CONCLUSION: The interatrial conduction time can be estimated with a relatively noninvasive method using P-LAA measurements. This technique can be applied widely in predicting AF recurrence, and appropriate therapy may be applied.
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Karaca et al. (2007) conducted a cross-sectional in Atrial conduction delay (n=33). Transesophageal echocardiography (P-LAA measurement) vs. Invasive electrophysiologic study (I-IACT measurement) was evaluated on Correlation between P-LAA and I-IACT (r = 0.839, p=< 0.0001). Transesophageal echocardiography measurement of P-LAA correlated strongly with invasive electrophysiologic measurement of interatrial conduction time (r = 0.839, P < 0.0001).
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