Key result
Pregnancy-associated MI occurs in ~3 per 100,000 pregnancies and carries a high case-fatality rate.
Why the study?
Cardiac disease is a leading cause of indirect maternal death, and the incidence, mortality, and case-fatality rates of pregnancy-associated myocardial infarction were not well characterized globally.
Meta-Analysis
Yes
Pregnancy-associated myocardial infarction is a rare but serious event with an incidence of 3.34 per 100,000 pregnancies and a 5% case-fatality rate, with rates rising over time especially in the USA.
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PAMI incidence informs peripartum vigilance; leaves open optimal prevention amid rising US trends.
Gibson et al. (2016) conducted a meta-analysis in Pregnancy-associated myocardial infarction. Pregnancy was evaluated on Pooled incidence of pregnancy-associated MI per 100,000 pregnancies (95% CI 2.09-4.58). The pooled incidence of pregnancy-associated myocardial infarction was 3.34 per 100,000 pregnancies (95% CI 2.09-4.58), with a case-fatality rate of 5.03%.
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