Key result
Food intake increases stroke volume ~23% versus fasting in CAD patients.
Why the study?
Does food intake alter central hemodynamic parameters in patients with coronary artery disease?
Population
36 patients with coronary artery disease
Comparison
Ingestion of a meal (food intake) vs Fasting
Design
Other
Follow-up
2 hours postprandially
Authors
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Postprandial hemodynamic changes may warrant monitoring in CAD; hypothesis-generating and requires prospective confirmation before clinical adoption.
Does food intake alter central hemodynamic parameters in patients with coronary artery disease?
Food intake induces positive inotropic and chronotropic effects in patients with coronary artery disease, likely driven by changes in intestinal vascular resistance and blood flow.
Henning Kelbæk (1989) studied Coronary artery disease (n=36). Food intake (ingestion of a meal) vs. Fasting was evaluated on Central hemodynamic parameters (stroke volume, heart rate, cardiac output, left ventricular ejection fraction). Food intake in patients with coronary artery disease increased stroke volume by 23% and heart rate by 8% at half an hour, with no significant hemodynamic changes in fasting patients.
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