Why the study?
Does a meal reduce exercise tolerance and alter hemodynamics compared to fasting in patients with chronic stable angina?
Population
23 patients with chronic stable angina who had post-prandial worsening of their angina
Comparison
1400 kcal meal given 60 minutes before a… vs Fasting state
Design
Other
Authors
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May link post-meal cardiac output rise to reduced exercise tolerance in angina; hypothesis-generating for targeted interventions.
Does a meal reduce exercise tolerance and alter hemodynamics compared to fasting in patients with chronic stable angina?
Post-prandial worsening of angina is related to an increase in cardiac output after a meal, suggesting that successful treatment depends on preventing this increase.
Cowley et al. (1991) studied this question.
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