Key result
Postprandial exercise linked to angina onset ~1.3 minutes sooner than preprandial exercise.
Why the study?
The mechanisms responsible for the more rapid precipitation of angina in the postprandial state were not well understood.
Does exercise following a meal accelerate the precipitation of angina compared to exercise before a meal in patients with angina?
Population
12 patients with angina
Comparison
Upright bicycle exercise after a meal vs before a meal
Design
Observational study
Authors
Loading...
Postprandial exercise may provoke earlier angina; leaves open whether meal timing should influence testing or activity guidance.
Observational (n=12)
Does exercise following a meal accelerate the precipitation of angina compared to exercise before a meal in patients with angina?
Mean Difference: 1.3
p-value: p=<0.001
The accelerated development of angina during exercise after meals is primarily driven by a more rapid rise in heart rate and blood pressure, which augments myocardial oxygen requirements.
Goldstein et al. (1971) conducted an observational in Angina pectoris (n=12). Meal consumption prior to exercise vs. Fasting state (before a meal) was evaluated on Time to development of angina during exercise (average 1.3 min sooner, p=<0.001). Exercising after a meal caused patients to develop angina an average of 1.3 minutes sooner than exercising before a meal (P<0.001), driven by a more rapid rise in heart rate and blood pressure.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: