Key result
Electrophysiological modeling supports cardiologists in understanding and managing AF, ischemia, and long-QT syndrome.
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Mathematical modeling of cardiac electrophysiology offers a promising tool to support the diagnosis and therapy of complex arrhythmias and ischemic conditions.
Simulations of the electrophysiological behavior of the heart improve the comprehension of the mechanisms of the cardiovascular system. Furthermore, the mathematical modeling will support diagnosis and therapy of patients suffering from heart diseases. In this paper, the chain of modeling of the electrical function in the heart is described. The components are explained briefly, namely modeling of cardiac geometry, reconstructing the cardiac electrophysiology and excitation propagation. Additionally, the mathematical methods allowing to implement and solve these models are outlined. The three recently more investigated cases atrial fibrillation, ischemia and long-QT syndrome are described and show how cardiac modeling can support cardiologists in answering their open questions.
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Seemann et al. (2010) conducted a review in Heart diseases (atrial fibrillation, ischemia, long-QT syndrome). Electrophysiological modeling was evaluated. Electrophysiological modeling of the heart can support cardiologists in understanding and managing conditions such as atrial fibrillation, ischemia, and long-QT syndrome.
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