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Mathematical and computer models of cardiac electrophysiology provide crucial insights into the mechanisms of heart failure, arrhythmias, and the optimization of cardiac resynchronization therapy.
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Mathematical modeling of cardiac electrophysiology provides crucial insights into the mechanisms of heart failure and the optimization of cardiac resynchronization therapy.
Next to clinical and experimental research, mathematical modeling plays a crucial role in medicine. Biomedical research takes place on many different levels, from molecules to the whole organism. Due to the complexity of biological systems, the interactions between components are often difficult or impossible to understand without the help of mathematical models. Mathematical models of cardiac electrophysiology have made a tremendous progress since the first numerical ECG simulations in the 1960s. This paper briefly reviews the development of this field and discusses some example cases where models have helped us forward, emphasizing applications that are relevant for the study of heart failure and cardiac resynchronization therapy.
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Mark Potse (2012) conducted a review in Heart failure and cardiac arrhythmias. Computer heart models was evaluated. Mathematical and computer models of cardiac electrophysiology provide crucial insights into the mechanisms of heart failure, arrhythmias, and the optimization of cardiac resynchronization therapy.
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