Key result
Preoperative hepatorenal dysfunction predicts ~14% higher mortality after isolated reoperative tricuspid valve surgery.
Why the study?
Reoperative tricuspid valve surgery is considered high risk even without concomitant procedures, prompting evaluation of preoperative clinical parameters to predict postoperative survival.
Does the MELD-XI score predict postoperative survival in patients undergoing isolated reoperative tricuspid valve surgery?
Population
85 patients with severe isolated TV regurgitation and prior cardiac surgery
Comparison
Preoperative hepatorenal function (including MELD-XI score) and clinical parameters
Design
Retrospective single-centre cohort study
Follow-up
Mean 5.4 ± 4.2 years
Authors
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The MELD-XI score and diabetes mellitus are significant predictors of mortality in patients undergoing isolated reoperative tricuspid valve surgery, highlighting the impact of hepatorenal dysfunction on outcomes.
Cohort (n=85)
No
Does the MELD-XI score predict postoperative survival in patients undergoing isolated reoperative tricuspid valve surgery?
Hazard Ratio: 1.144 (95% CI 1–1.3)
p-value: p=0.005
The MELD-XI score and diabetes mellitus are significant predictors of mortality in patients undergoing isolated reoperative tricuspid valve surgery, highlighting the impact of hepatorenal dysfunction on outcomes.
Pfannmueller et al. (2021) conducted a cohort in severe isolated tricuspid valve regurgitation and prior cardiac surgery (n=85). Preoperative hepatorenal dysfunction (MELD-XI score) was evaluated on mortality (HR 1.144, 95% CI 1.0-1.3, p=0.005). Preoperative hepatorenal dysfunction, assessed by the MELD-XI score, significantly predicted excess mortality after isolated reoperative tricuspid valve surgery (HR 1.144; 95% CI 1.0-1.3; P=0.005).
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