What does this research mean for the field?

The proximal isovelocity surface area (PISA) method accurately measures mitral regurgitation volume in dogs with severe mitral insufficiency, demonstrating strong correlation with pulsed Doppler echocardiography. Novelty: ClaimNovelty.CONFIRMATORY. Consensus alignment: ConsensusAlignment.NEUTRAL.

January 1, 2000Journal of Veterinary Medical ScienceOpen Access

Examination of Quantitative Analysis and Measurement of the Regurgitation Rate in Mitral Valve Regurgitation by the "Proximal Isovelocity Surface Area" Method.

Q: What are the key findings of this study?

The PISA method demonstrated a strong correlation (r=0.97, p<0.01) with the pulsed Doppler method for measuring regurgitation volumes in dogs with severe mitral valve insufficiency.

Q: What is the clinical evidence from this study?

Study design: Cross-Sectional. Population: Mitral valve insufficiency (n=33). Intervention: Proximal Isovelocity Surface Area (PISA) method vs. Pulsed Doppler method. Primary outcome: Correlation of regurgitation volumes between PISA and pulsed Doppler methods (r=0.97, p=<0.01).

View Full Paper

Ask AI

Bookmark

Key result

PISA strongly correlates with pulsed Doppler for measuring severe mitral regurgitation volumes in dogs.

r=0.97
P<0.01
n=33

Why the study?

Accurate quantitative measurement of regurgitation rate in severe mitral valve regurgitation using the PISA method required evaluation and validation.

Does the PISA method correlate with the pulsed Doppler method for measuring regurgitation volumes in dogs with severe mitral valve insufficiency?

Study Design

Type

Cross-Sectional (n=33)

Multicenter

Yes

Structured PICO

Does the PISA method correlate with the pulsed Doppler method for measuring regurgitation volumes in dogs with severe mitral valve insufficiency?

Population

33 dogs (mean age 10.8 years, 36.4% female) with severe mitral valve insufficiency evaluated to compare regurgitation volumes measured by the PISA and pulsed Doppler methods.

Intervention

Measurement of regurgitation volumes by the 'Proximal Isovelocity Surface Area' (PISA) method

Comparator

Measurement by pulsed Doppler method

Outcome

Correlation between regurgitation volumes determined by PISA and pulsed Doppler methodssurrogate

Main Result

Effect estimate: r=0.97

p-value: p=<0.01

The PISA method shows excellent correlation with the pulsed Doppler method for quantifying regurgitation volume in a canine model of severe mitral valve insufficiency.

Limitations

Overestimates regurgitation when aliasing velocity forms a near-circle in severe mitral valve degeneration and prolapse.
Underestimates regurgitation when aliasing velocities of the acceleration flow forms are not clearly represented.
The method should only be used when the acceleration flow forms a clear semicircle.

Implication

Supports PISA validation in canine mitral regurgitation models; leaves open clinical translation in veterinary practice.

Abstract

In 33 dogs with mitral valve insufficiency (MR), assessed as severe by semi-quantitative color flow Doppler echocardiography, regurgitation volumes were measured by the "Proximal Isovelocity Surface Area" (PISA) method. Good correlation (p<0.01, r=0.97) between the regurgitation volumes determined by the "PISA" and pulsed Doppler methods was confirmed. As evaluated by the "PISA" method, regurgitation rates in the 32 dogs with measurable regurgitation volumes ranged from 23 to 73%, with a mean of 51.6 +/- 11.8%. Regurgitation volumes ranged from 3.3 to 32 ml, with a mean of 8.4 +/- 6.4 ml.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Doiguchi et al. (2000) conducted a cross-sectional in Mitral valve insufficiency (n=33). Proximal Isovelocity Surface Area (PISA) method vs. Pulsed Doppler method was evaluated on Correlation of regurgitation volumes between PISA and pulsed Doppler methods (r=0.97, p=<0.01). The PISA method demonstrated a strong correlation (r=0.97, p<0.01) with the pulsed Doppler method for measuring regurgitation volumes in dogs with severe mitral valve insufficiency.

synapsesocial.com/papers/6aa851e485349d04753e1480 https://doi.org/10.1292/jvms.62.109

Topics

Mitral valve intervention

View Full Paper

Ask AI

Bookmark

Implication

Supports PISA validation in canine mitral regurgitation models; leaves open clinical translation in veterinary practice.

Examination of Quantitative Analysis and Measurement of the Regurgitation Rate in Mitral Valve Regurgitation by the "Proximal Isovelocity Surface Area" Method.

Study Design

Structured PICO

Main Result

Limitations

Implication

Abstract

Discussion

Cite This Study

Topics

Examination of Quantitative Analysis and Measurement of the Regurgitation Rate in Mitral Valve Regurgitation by the "Proximal Isovelocity Surface Area" Method.

Study Design

Structured PICO

Main Result

Limitations

Implication

Abstract

Discussion

Cite This Study

Keep reading

Topics

Keep reading