Why the study?
Coeliac patients face risk from unintentional gluten contamination or hidden gluten in food products, prompting a review of gluten risk analysis and immunological detection methods.
Comparison
Immunological methods currently used in gluten detection vs other analytical methods
Design
Review
Key result
Immunological methods like ELISAs are suitable for routine gluten detection, but their reliability is affected by food matrix complexity, antibody type, and lack of reference materials.
Authors
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Urges caution interpreting ELISA gluten results in complex foods; leaves open need for harmonized reference materials.
Immunological methods are suitable for routine gluten detection but require harmonization to overcome analytical drawbacks and ensure safe food choices.
Melini et al. (2018) conducted a review in Coeliac disease and gluten-related disorders. Immunological methods for gluten detection was evaluated. Immunological methods like ELISAs are suitable for routine gluten detection, but their reliability is affected by food matrix complexity, antibody type, and lack of reference materials.
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