Key result
The immunochromatographic test demonstrated 90% sensitivity, 98% specificity, and excellent agreement (Kappa 0.89) with the R5-ELISA method for detecting gluten at safe levels in foods labeled gluten-free.
Why the study?
Does the immunochromatographic test reliably detect gluten in gluten-free labeled foods compared to the R5-ELISA method?
Population
70 different commercially available foods in Brazil labeled "gluten-free" or containing naturally…
Comparison
Immunochromatographic test for gluten detection vs R5-ELISA kit for gluten detection
Design
Other
Authors
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The immunochromatographic method is a sensitive, inexpensive, and rapid alternative to R5-ELISA for detecting gluten, revealing that over 25% of "gluten-free" labeled foods in Brazil contain detectable gluten.
Cross-Sectional (n=70)
Does the immunochromatographic test reliably detect gluten in gluten-free labeled foods compared to the R5-ELISA method?
Effect estimate: Kappa 0.89
Absolute Event Rate: 27.1% vs 28.6%
p-value: p=1.00
The immunochromatographic method is a sensitive, inexpensive, and rapid alternative to R5-ELISA for detecting gluten, revealing that over 25% of "gluten-free" labeled foods in Brazil contain detectable gluten.
Laureano et al. (2015) conducted a cross-sectional in Celiac disease (Gluten-free food analysis) (n=70). Immunochromatographic test vs. R5-ELISA test was evaluated on Agreement between immunochromatographic test and R5-ELISA at a 5 mg/kg gluten detection cutoff (Kappa 0.89, p=1.00). The immunochromatographic test demonstrated 90% sensitivity, 98% specificity, and excellent agreement (Kappa 0.89) with the R5-ELISA method for detecting gluten at safe levels in foods labeled gluten-free.
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