Key result
Skin tags correlate with an atherogenic lipid profile featuring high triglycerides and low HDL.
Why the study?
Skin tags may be associated with an atherogenic lipid profile linked to insulin resistance, type 2 diabetes mellitus, and increased cardiovascular risk, but this relationship is not well characterized.
Are skin tags associated with an atherogenic lipid profile and increased cardiovascular risk?
Case Report (n=4)
Are skin tags associated with an atherogenic lipid profile and increased cardiovascular risk?
Answers are grounded in this paper and cite their sources.
Skin tags may serve as a simple clinical sign to prompt screening for atherogenic dyslipidemia, type 2 diabetes, and cardiovascular disease.
This report details four patients who had skin tags, mainly on their torso, neck, and axillae, and who also displayed an abnormal lipid profile. All showed an increased serum triglyceride (fasting > 1.70 mmol/litre) and a decreased high density lipoprotein (HDL) cholesterol (< 1.1 mmol/litre in women and 1.0 mmol/litre for men) concentration. The displayed lipid profile is also known as the atherogenic profile and is associated with insulin resistance, type 2 diabetes mellitus, and an increased risk of cardiovascular disease. Two of the patients had impaired glucose tolerance and one had type 2 diabetes mellitus. Three of the individuals had coronary artery disease. Skin tags might be a useful clinical sign that could alert clinicians to screen such individuals for abnormal lipids, type 2 diabetes mellitus, and cardiovascular disease.
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Martin Crook (2000) conducted a case report in Skin tags and abnormal lipid profile (n=4). Skin tags was evaluated on Atherogenic lipid profile (increased serum triglyceride and decreased HDL cholesterol).
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