Key result
TAVI is linked to ~5-fold greater operative mortality than surgery, highlighting EuroSCORE and ACEF utility.
Why the study?
The accuracy and calibration of EuroSCORE and ACEF score in selecting patients for TAVI and their limitations in accounting for extreme risk conditions were uncertain.
Do the EuroSCORE and ACEF score accurately predict operative mortality in patients referred for surgical or transcatheter aortic valve procedures?
Population
1053 surgical and 211 transcatheter aortic valve procedure patients
Comparison
EuroSCORE vs ACEF score for risk stratification
Design
Multicenter retrospective observational study
Authors
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May support EuroSCORE and ACEF for TAVI referral; leaves open need for TAVI-specific models incorporating extreme risks.
Observational (n=1,264)
Yes
Do the EuroSCORE and ACEF score accurately predict operative mortality in patients referred for surgical or transcatheter aortic valve procedures?
Absolute Event Rate: 10.4% vs 2%
Both the EuroSCORE and ACEF score can be used to refer patients to TAVI, but they lack integration of extreme risk conditions, highlighting the need for TAVI-specific risk models.
Ranucci et al. (2010) conducted an observational in Severe aortic stenosis (n=1,264). Transcatheter aortic valve implantation (TAVI) vs. Surgical aortic valve replacement was evaluated on Operative mortality. Transcatheter aortic valve implantation had an observed mortality rate of 10.4% compared to 2.0% for surgical replacement, with EuroSCORE and ACEF scores showing utility for patient referral.
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