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Shows rapid reduction of blood pressure and catecholamines with belzutifan in paraganglioma, indicating targeted cardiovascular symptom control.
Many patients with pheochromocytoma and paraganglioma have hypertension from tumor-derived catecholamines. The HIF-2α inhibitor belzutifan rapidly reduced blood pressure and excess catecholamine levels.
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Alkaissi et al. (2024) studied this question.
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