Key result
Pediatric cardiac valve replacement carries ~12% operative mortality, especially in children under two and repeat surgeries.
Why the study?
Valve replacement in children is a high-risk procedure with limited data on outcomes and anticoagulation management in this population.
Comparison
Mechanical valves with anticoagulation vs mechanical valves without anticoagulation
Design
Single-center case series
Authors
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Highlights high perioperative risk in pediatric valve replacement; leaves open need for multicenter data to refine strategies.
Cohort (n=94)
No
Cardiac valve replacement in children is a high-risk procedure with 12% operative mortality, and anticoagulation is strongly recommended for mechanical prostheses to prevent high rates of thromboembolic events.
Robbins et al. (1988) conducted a cohort in Cardiac valve replacement (n=94). Cardiac valve replacement was evaluated on Operative mortality. Cardiac valve replacement in children carried an overall operative mortality of 12%, with higher risk in those under 2 years, with prior cardiac operations, or requiring double-valve replacement.
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