Key result
Postrepair coaptation height ≥8 mm predicts freedom from residual aortic regurgitation after valve-sparing root replacement.
Why the study?
The study was conducted to identify quantitative criteria to avoid residual aortic valve regurgitation after valve-sparing aortic root replacement.
Does achieving a specific cusp coaptation height prevent residual aortic regurgitation in adult patients undergoing valve-sparing aortic root replacement?
Observational (n=562)
Yes
Does achieving a specific cusp coaptation height prevent residual aortic regurgitation in adult patients undergoing valve-sparing aortic root replacement?
A target cusp coaptation height of at least 8 to 9 mm during valve-sparing aortic root replacement is a key quantitative criterion to predict freedom from residual aortic regurgitation.
Answers are grounded in this paper and cite their sources.
May inform cusp coaptation targets during valve-sparing root replacement; hypothesis-generating and needs prospective validation.
Objective The study objective was to identify quantitative criteria to avoid residual aortic valve regurgitation after valve-sparing aortic root replacement. Methods Between 2016 and 2023, 738 adult patients were recruited into the German Aortic Root Repair Registry. A total of 562 patients with datasets on aortic root measurements and tricuspid valve treated with reimplantation valve-sparing aortic root replacement were selected. End points were any grade of residual aortic valve regurgitation and postrepair coaptation height. Tested variables included procedural and anatomic characteristics, including length of cusp margins and geometric cusp heights. Results The optimal classifier predicting freedom from residual aortic valve regurgitation was cusp coaptation height 8 to 9 mm or more (sensitivity = 0.7-0.8). Annular downsizing alone was not useful to predict residual aortic valve regurgitation ( P = .472, 95% area CI, 0.414-0.54). Patients with a mean free margin length of at least 45 mm and a sum of free margin lengths of at least 125 mm were more likely to present coaptation heights of at least 10 mm (R2 0.038, P = .006). Conclusions The target coaptation height after valve-sparing aortic root replacement should exceed 8 to 9 mm. Chances of achieving it can be estimated on the basis of a measurement of cusp quantity. If in doubt when inspecting a valve, numerical criteria can help with surgical decision-making in favor of or against a valve-sparing approach.
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Kari et al. (2025) conducted an observational in Aortic root disease (n=562). Reimplantation valve-sparing aortic root replacement was evaluated on Any grade of residual aortic valve regurgitation and postrepair coaptation height. A postrepair cusp coaptation height of ≥8 to 9 mm optimally predicted freedom from residual aortic valve regurgitation after valve-sparing aortic root replacement.
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