Key result
Age, sex, and aortic stenosis severity, not bicuspid valve morphology, predict aortic dilatation.
Why the study?
The association between morphological and functional characteristics of the bicuspid aortic valve and bicuspid aortopathy, as well as determinants of aortic dilatation, needed to be identified.
Are morphological and functional characteristics of the bicuspid aortic valve associated with aortic dilatation?
Observational (n=312)
Are morphological and functional characteristics of the bicuspid aortic valve associated with aortic dilatation?
In patients with bicuspid aortic valves, aortic dilatation is predicted by age, sex, and aortic stenosis severity rather than valve morphology.
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Age, sex, and AS severity predict bicuspid aortopathy independent of valve morphology; leaves open whether morphology informs risk stratification.
Choi et al. (2021) conducted an observational in Bicuspid aortic valve and bicuspid aortopathy (n=312). Morphological and functional characteristics of the bicuspid aortic valve was evaluated on Aortic root and proximal ascending aortic dilatation (size index > 2.1 cm/m²). Age, sex, and aortic stenosis severity, rather than bicuspid aortic valve morphology, were predictors of aortic root and ascending aortic dilatation.
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