Key result
Type I bicuspid aortic valve morphology was associated with increased aortic dimension at the sinuses of Valsalva compared to type II (38.4 vs. 34.0 mm, p=0.002).
Why the study?
Does Type I BAV morphology compared to Type II BAV morphology increase aortic dilatation in patients with bicuspid aortic valves?
Observational (n=1,067)
No
Does Type I BAV morphology compared to Type II BAV morphology increase aortic dilatation in patients with bicuspid aortic valves?
Absolute Event Rate: 38.4% vs 34%
p-value: p=0.002
Type I bicuspid aortic valve morphology (right-left coronary cusp fusion) is more strongly associated with aortic dilatation at the sinus of Valsalva and ascending aorta compared to Type II morphology.
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May inform morphology-specific aortic surveillance in BAV; leaves open independent risk and need for prospective validation.
Miśkowiec et al. (2015) conducted an observational in Bicuspid aortic valve (n=1,067). Type I bicuspid aortic valve morphology vs. Type II bicuspid aortic valve morphology was evaluated on Aortic dimension at the level of the sinuses of Valsalva (p=0.002). Type I bicuspid aortic valve morphology was associated with increased aortic dimension at the sinuses of Valsalva compared to type II (38.4 vs. 34.0 mm, p=0.002).
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