Key result
Higher heart rate is linked to a linearly increased prevalence of metabolic syndrome.
Why the study?
Autonomic dysfunction is considered an important mechanism of metabolic syndrome, but the direct association between metabolic syndrome and heart rate in Japanese had not been studied.
Is heart rate associated with the prevalence of metabolic syndrome and its related risk factors in Japanese individuals?
Cross-Sectional (n=2,959)
No
Is heart rate associated with the prevalence of metabolic syndrome and its related risk factors in Japanese individuals?
p-value: p=<0.0001
Higher resting heart rate is linearly associated with an increased prevalence of metabolic syndrome and its related risk factors in Japanese men and women.
May aid metabolic syndrome risk stratification in Japanese adults; hypothesis-generating and should not yet change practice.
BACKGROUND: Autonomic dysfunction is thought to be an important mechanism of metabolic syndrome (MetS), but there has not been a study on the direct association between MetS and heart rate (HR) in Japanese. METHODS AND RESULTS: The association between MetS and HR was examined using medical check-up data from 1,880 men and 1,079 women. HR was significantly higher in MetS subjects than in non-MetS subjects in both men and women (P<0.0001 in men, P<0.001 in women). The prevalence of MetS increased linearly through the quartiles of HR in both men and women. HR was significantly correlated with MetS-related risk factors other than uric acid in men and other than uric acid, body mass index, waist circumference, and high-density lipoprotein cholesterol in women. CONCLUSIONS: The prevalence of MetS increased linearly with the increase in HR among Japanese men and women, and HR was significantly correlated with MetS-related risk factors.
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Oda et al. (2009) conducted a cross-sectional in Metabolic Syndrome (n=2,959). Heart rate vs. Lower quartiles of heart rate was evaluated on Prevalence of metabolic syndrome across quartiles of heart rate (p=<0.0001). Higher heart rate was significantly associated with a linearly increased prevalence of metabolic syndrome and its related risk factors in both Japanese men and women.
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