Key result
Technical Performance Score Class 3 linked to ~8-fold more post-discharge mitral reinterventions after congenital repair.
Why the study?
Does the Technical Performance Score predict midterm mortality and reinterventions in congenital patients undergoing mitral valve repair?
Cohort (n=587)
Does the Technical Performance Score predict midterm mortality and reinterventions in congenital patients undergoing mitral valve repair?
Hazard Ratio: 8.7 (95% CI 3–25.1)
p-value: p=<0.001
The Technical Performance Score based on predischarge echocardiograms and reinterventions is a strong predictor of midterm mortality and post-discharge mitral reintervention in pediatric patients undergoing congenital mitral valve repair.
May support intensified surveillance after congenital mitral repair in TPS Class 3; leaves open prospective validation before practice change.
OBJECTIVES: The Technical Performance Score (TPS) has been shown to be predictive of postoperative mortality, morbidities and reinterventions following various cardiac procedures in children. We hypothesized that TPS is also a predictor of mitral valve repair outcomes. METHODS: A review of patients who underwent mitral valve repair from January 2000 to December 2013 was performed. Primary repair of complete atrioventricular defect was excluded. The scores were determined according to previously published criteria based on the need for reintervention and predischarge echocardiograms: Class 1 (no residua), Class 2 (minor residua) or Class 3 (pacemaker implantation, major residua or reintervention for major residua prior to discharge). Cox proportional hazard models and Kaplan-Meier estimator were used. RESULTS: A total of 587 patients underwent mitral repair (median age 2.6 years). Median follow-up duration was 3 years. There were 125 (21.3%) post-discharge mitral reinterventions and freedom from reintervention was 85.2%, 78.2% and 69.4% at 1, 2 and 5 years, respectively. Both TPS Class 2 [hazard ratio (HR) 3.6, 95% confidence interval (CI) 1.4-10.0; P = 0.02] and Class 3 (HR 8.7, 95% CI 3.0-25.1; P < 0.001) were associated with post-discharge reinterventions. There were 31 late deaths/transplantations, and transplant-free survival at 1, 2 and 5 years was 97.8%, 95.3% and 93.2%. TPS 3 was associated with decreased post-discharge transplant-free survival (HR 5.5, 95% CI 1.2-25.0; P = 0.03). Post-discharge mitral reintervention was not associated with increased mortality. CONCLUSIONS: The TPS is a strong predictor of midterm mortality and post-discharge mitral reintervention in congenital patients who underwent mitral repair.
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Martin et al. (2017) conducted a cohort in Congenital mitral valve disease (n=587). Technical Performance Score (TPS) Class 3 vs. TPS Class 1 (no residua) was evaluated on Post-discharge mitral reinterventions (HR 8.7, 95% CI 3.0-25.1, p=<0.001). Technical Performance Score Class 3 was strongly associated with increased post-discharge mitral reinterventions (HR 8.7; 95% CI 3.0-25.1; P<0.001) following congenital mitral valve repair.
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