Key result
30-J biphasic discharges reduce postshock R wave amplitude more in integrated than true bipolar leads.
Why the study?
Do high-energy biphasic shocks reduce postshock R wave amplitude more in integrated versus true bipolar nonthoracotomy lead systems?
Do high-energy biphasic shocks reduce postshock R wave amplitude more in integrated versus true bipolar nonthoracotomy lead systems?
High-energy shocks cause significant, time-dependent reductions in postshock R wave amplitude, particularly in integrated bipolar lead systems, which may delay arrhythmia redetection.
High-energy shocks may impair postshock sensing more with integrated leads; hypothesis-generating for lead selection in ICDs.
INTRODUCTION: The purpose of this investigation was to prospectively evaluate the voltage- and time-dependent characteristics of a biphasic defibrillator discharge on the amplitude of the rate sensing electrogram recorded from two "integrated" and one true bipolar nonthoracotomy lead system. Prolongation of redetection time has been noted after a failed first shock with nonthoracotomy lead systems. However, a prospective evaluation of the time- and voltage-dependent effects of biphasic shocks on electrogram amplitude with clinically utilized lead systems has not been systematically performed. METHODS AND RESULTS: Five- then 30-J R wave synchronous biphasic discharges were delivered during the supraventricular rhythm through three nonthoracotomy lead systems (Medtronic Transvene, Ventritex TVL, and CPI Endotak C 60 Series). The R wave amplitude was measured immediately postshock and for up to 1 minute. Amplitude changes were compared with preshock baseline value. A 5-J discharge had minimal effect on the R wave amplitude recorded from the three lead systems; however, 30 J resulted in significant diminution in R wave amplitude recorded from the integrated bipolar leads (in the Endotak lead to a greater extent than the TVL lead) with minimal effects on the Transvene lead. Following a 30-J discharge, the time constant for R wave recovery was 4.2, 14.9, and 15.3 seconds for Transvene, TVL, and Endotak 60 leads, respectively. CONCLUSION: There are voltage- and time-dependent reductions in postshock R wave amplitude. Integrated bipolar systems appear more affected than the "true" bipolar lead evaluated. This may be due, in part, to lead design, distance of distal defibrillating surface from rate sensing cathode, and the incorporation of the defibrillating surface as the rate sensing anode. The influence of post-shock R wave diminution on subsequent redetection remains speculative but may have implications for subsequent lead development.
No takes yet. Share an insight, caveat, or question.
Gottlieb et al. (1996) studied this question. Biphasic defibrillator discharges via nonthoracotomy lead systems vs. Preshock baseline was evaluated on R wave amplitude changes and time constant for R wave recovery. A 30-J biphasic discharge caused significant reductions in postshock R wave amplitude, with integrated bipolar leads (Endotak, TVL) more affected than true bipolar leads (Transvene).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: